Bill Sardi
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 Journal alzheimer's disease 7, 273-84, 2005] Long-term exposure to low levels of aluminum in animals raises levels of an enzyme (acetycholinesterase) that facilitates memory loss in alzheimer's disease. [Journal Inorganic Biochemistry 99:1865-70, 2005] Public health authorities may give aluminum a clean bill of health in regard to cancer, but need to warn the public there are other health concerns involving aluminum.
Is cancer contagious? |
James Dowd and Diane Stafford
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 People with alzheimer's disease who have early comprehension troubles that progress to dementia quickly usually have very low vitamin D levels. Experts believe that low D levels probably play a role in the progression of dementia.
A person in the late stages of Parkinson's disease also may have dementia that's much like that seen in alzheimer's disease. The dysfunctional movements of Parkinson's disease point to the source of the problem in an area at the base of the brain that coordinates movement. This region of the brain has a very high concentration of vitamin D receptors. |
Bill Sardi
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| Journal alzheimer's disease 7, 273-84, 2005] Long-term exposure to low levels of aluminum in animals raises levels of an enzyme (acetycholinesterase) that facilitates memory loss in alzheimer's disease. [Journal Inorganic Biochemistry 99:1865-70, 2005] Public health authorities may give aluminum a clean bill of health in regard to cancer, but need to warn the public there are other health concerns involving aluminum.
Is cancer contagious? |
Elaine Magee
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 A recent study of New Yorkers by the Taub Institute for Research on alzheimer's disease and the Aging Brain at Columbia University Medical Center found that closely following the patterns of the Mediterranean diet was associated with a lower risk of alzheimer's disease. More needs to be known about this possible food synergy benefit, but so far this looks like another reason to eat the Mediterranean way!
Reduce levels of oxidized LDL in the circulation. |
Jonny Bowden, Ph.D., C.N.S.
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 Finally, numerous studies have cited the connection between inflammation, oxidation, and alzheimer's disease. Antioxidants have a potent role in the prevention of neurodegenerative diseases. One study, "A review of antioxidants and alzheimer's disease," published in the Annals of Clinical Psychiatry in 2005, reviewed all the research published to date in order to draw conclusions about the usefulness (or lack thereof) of specific antioxidants in the prevention of Alzheimer's. |
Gabriel Cousens
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 Studies show that alpha-lipoic acid (ALA) helps protect the brain against damage caused by free-radical-induced oxidative stress, which has important implications for its potential role in protecting against alzheimer's disease.147'148
Other good news is that the high blood sugar of diabetes and the increased risk for Alzheimer's is related to consumption of processed high-glycemic foods, not natural foods. Juicy new research suggests that antioxidants in fruit and vegetable juices may lower the risk of alzheimer's disease. |
Tom Bohager
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 The symptoms of alzheimer's disease are progressive mental deterioration characterized by an inability to carry out daily activities, a loss of cognitive functions, and a loss of memory functions. Extensive research studies indicate that the causes of alzheimer's disease can include genetic factors, age, environmental factors, chronic exposure to aluminum and/or silicon, and increased oxidative damage due to long-term toxic exposure. |
Gabriel Cousens
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| Soy may also be connected with alzheimer's disease, now thought to be a complication of hyperglycemia and diabetes. In a major ongoing study involving 3,734 elderly Japanese American men, those who ate the most tofu during midlife had up to 2.4 times the risk of later developing alzheimer's disease. As part of the three-decade-long Honolulu-Asia Aging Study, twenty-seven foods and drinks were correlated with participants' health. Men who consumed tofu at least twice weekly had more cognitive impairment than those who rarely or never ate the soybean curd. |
Elaine Magee
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| A recent study of New Yorkers by the Taub Institute for Research on alzheimer's disease and the Aging Brain at Columbia University Medical Center found that closely following the patterns of the Mediterranean diet was associated with a lower risk of alzheimer's disease. More needs to be known about this possible food synergy benefit, but so far this looks like another reason to eat the Mediterranean way!
Reduce levels of oxidized LDL in the circulation. |
Jonny Bowden, Ph.D., C.N.S.
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| Helps keep fatty deposits from collecting on arteries, thus preventing heart attacks, strokes, premature aging, alzheimer's disease, and cancer.
4. Olive oil (extra virgin): A natural anti-inflammatory much like aspirin or ibuprofen. It reduces the risk of stroke, heart and cardiovascular disease, breast cancer, lung cancer, and some forms of dementia.
5. Nuts: Great source of dietary fiber, antioxidants, magnesium, copper, folic acid, vegetable protein, potassium, vitamin E, and healthy fats, all of which help reduce the risk of heart disease.
6. |
Bottom Line Health
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| The medication donepezil (Aricept), which is typically used to treat mild to moderate alzheimer's disease, seems to reverse some cognitive and functional deterioration in patients who have severe forms of the disease, Swedish researchers report.
Approximately 20% of Alzheimer's patients have severe dementia, but the potential benefit of using Aricept to treat them had not been studied until now.
THE STUDY
In the trial, a research team led by Dr. |
Dr. Sharon Moalem
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 In Caucasians, it even carries a higher risk for development of alzheimer's disease.
And as you've seen with iron loading and diabetes—one generation's evolutionary solution is another generation's evolutionary problem, especially when people no longer live in the environment that their bodies adapted to through evolution. (If you want a funny-sounding example of an environmental defense turned environmental hazard, you need look no further than your nose. |
Mehmet C. Oz., M.D. and Michael F. Roizen, M.D.
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 That's important because alzheimer's disease takes decades to develop. The amazing part was that even if the nuns showed pathological signs of Alzheimer's, they had no clinical symptoms. The point: Although these neurological tangles may be genetic, your ability to resist the effects of them is not.
When you increase your learning during life, you decrease the risk of developing memory-related problems. That means your brain has a fighting chance if you keep it active and engaged, if you keep challenging it with new lessons, if you learn a new game or new hobby or new vocation. |
Jonny Bowden, Ph.D., C.N.S.
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| Acetylcholine is critical for memory and thought; according to the Physicians' Desk Reference, adequate acetylcholine levels in the brain are believed to be protective against certain types of dementia, including alzheimer's disease. So eggs— like fish—are truly brain food!
Eggs for Healthy Eyes
Eggs are also "eye" food. Eggs contain lutein and zeaxanthin, two of the new "superstar" nutrients when it comes to eye health. Lutein, present in the macula of the eye's retina, appears to filter harmful, high-energy blue wavelengths of visible light from both natural sunlight and indoor light. Dr. |
Dr. Sharon Moalem
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| It was a complex genetic association, but sure enough there was indeed a link between hemochromatosis and certain types of alzheimer's disease.
It was a bittersweet victory, though. I had proved my high school hunch (and even earned a Ph.D. for it), but it did nothing for my grandfather. He had died twelve years earlier, at seventy-six, after five long years battling Alzheimer's. Of course, I also knew that this discovery could help many others—and that's why I wanted to be a physician and a scientist in the first place. |
Jonny Bowden, Ph.D., C.N.S.
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| It may also inhibit beta-amyloid fibril formation, a key problem with alzheimer's disease. worth thinking about
Raisins are a great example of what I call the "fallacy of the perfect friend." All of us have a pal who's really great for doing certain things with, but not so great for other things. For example, we might have a friend whom we can really open up to about our feelings, but maybe that friend is kind of useless when we're looking for a tennis partner. Food is a lot like that. Some are really good for some things, but not so great for others. Raisins, for example. |
Dr. Sharon Moalem
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| Alzheimer's disease. He was seventy-one. Alzheimer's—as too many people know—is a terrible disease to watch. And when you're fifteen, watching a strong, loving man drift away almost before your eyes, it's hard to accept. You want answers. You want to know why.
Now, there was one thing about my grandfather that always struck me as kind of strange—he loved to give blood. And I mean he loved it. He loved the way it made him feel; he loved the way it energized him. |
Jonny Bowden, Ph.D., C.N.S.
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| One study, "A review of antioxidants and alzheimer's disease," published in the Annals of Clinical Psychiatry in 2005, reviewed all the research published to date in order to draw conclusions about the usefulness (or lack thereof) of specific antioxidants in the prevention of Alzheimer's. The researchers scanned more than 300 articles and concluded that there were eight agents that showed promise in helping prevent Alzheimer's. Green tea was one of the eight (the other seven were aged garlic, curcumin, melatonin, resveratrol, Gingko biloba, vitamin C, and vitamin E). |
Too Profitable to CureBrent Hoadley, Ph.D.
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| Visit with a family caring for a loved one with alzheimer's disease. These are all impacted by the manner in which the pharmaceuticals deal with the consumer.
An actionable goal must be established based on the well-being of humanity. If you believe the maxim that "He who dies with the most toys wins/' you might be more comfortably aligned with pharmaceutical CEOs and government big-wigs. Remember, though, that even these "winners" die, and as far as anyone knows, they don't take their "winnings" with them. |
Dr. Paula Baillie-Hamilton
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 Walter Kukull, Professor of Epidemiology, University of Washington School of Public Health and Community Medicine, found that people who had worked with organic solvents, such as benzene, toluene, phenols, alcohols, and ketones in the past were more at risk of developing alzheimer's disease.
Finally, people who have alzheimer's disease have been found to have higher levels of certain metals in their brains and in their bloodstream, including substances such as aluminum, mercury, iron, and copper. |
Mehmet C. Oz., M.D. and Michael F. Roizen, M.D.
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| Research shows that you can do things to improve your levels of BDNF, such as consuming the spice curcumin (a component of turmeric), restricting calories, doing exercise, being in love, and taking some of a class of antidepressants known as selective serotonin reuptake inhib-
FACTOIP
Those neurofibrillary tangles associated with alzheimer's disease contain aluminum (an element that makes up 14 percent of the earth's crust). While there's no evidence suggesting that aluminum causes memory problems, it's better to try to avoid it. |
| Especially avoid aluminum, which is found in high levels in the brain plaques linked to alzheimer's disease. And with deodorants, avoid phtha-lates, which are plastics used to help the fragrance stay on our skin and block endocrine function, especially in the male fetus. Parabens, which are used as preservatives in these products, should also be avoided since they could be linked to breast cancer.
Avoid air fresheners, which have gaseous chemicals like those found in moth balls, and the hockey-puck-shaped deodorants in urinals (for those readers lucky enough to frequent the male restroom). |
Bottom Line Health
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| In a previous study, Morris found that DHA reduced the risk of developing alzheimer's disease. "DHA is very important for the communication between neurons and the overall functioning of neurons," she explains.
THE JURY IS STILL OUT
At least one expert thinks this study does not make a conclusive case that DHA—or any other omega-3 fatty acid, for that matter—is the reason that fish consumption appears to slow a decline in thinking ability.
Greg M. |
| Adequate levels may even prevent alzheimer's disease. Researchers at the Picower Center for Learning and Memory at the Massachusetts Institute of Technology found that magnesium affects the synapses—connections between brain cells—by improving their plasticity, or ability to adapt to change, which usually declines with age.
Most people don't get enough magnesium. An adult's daily nutritional requirement is 400 milligrams (mg), but a survey conducted by the Centers for Disease Control and Prevention (CDC) found that the average intake is approximately 290 mg. Here's how magnesium can help you.. |
Hyla Cass, M.D.
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 In my own clinical experience, elderly individuals that appeared to have alzheimer's disease have responded remarkably well to a series of B12 and folic acid injections, showing an increase in memory, thinking ability, and mood.
Dose: 500-1,000 meg daily. Folic Acid/Folate
Folic acid, also known as folate, also helps to prevent depression. Fifteen to thirty-eight percent of adults diagnosed with depressive disorders have been found to have borderline low or deficient blood levels of folic acid. |
Bottom Line Health
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| Although scientific evidence is not sufficient to prove that this amyloid accumulation is the main cause of alzheimer's disease, many researchers believe that it is.
THE RESEARCH
The researchers sought to design a vaccine —administered via drops in the nose—that would initiate an amyloid-cleansing process by triggering the immune system without provoking antibody development, a problem that occurred in previous trials.
Study coauthor Dr. Howard L. |
The Editors of FC&A
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| In our study, we found that low levels of either of these two vitamins were related to an increased alzheimer's disease risk," says Hui-Xin Wang, a researcher with the Swedish Kungsholmen Project. His study monitored the levels of these vital nutrients in 370 healthy people age 75 and older for three years.
People with low amounts of B12 and folate had higher homocysteine levels. This is particularly important because one study found that people with high levels of homocysteine were at an almost three times greater risk for alzheimer's disease than those with low levels. |
Bottom Line Health
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| This work ties several concepts together and demonstrates that alzheimer's disease is quite possibly a type 3 diabetes," she says. (To understand the differences between type 1 and type 2 diabetes, see page 76.)
This study may have treatment implications, such as using certain types of antidiabetes drugs to treat and/or prevent Alzheimer's.
OTHER FACTORS
Dr. Hugh C. |
Joerg Gruenwald, Ph.D.
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 Its use in the treatment of alzheimer's disease to reduce memory loss and confusion is being investigated.
PRECAUTIONS AND ADVERSE REACTIONS
The drug is only used in the extraction of physostigmine. Symptoms of poisoning include: diarrhea, nausea, salivation, sweats and vomiting.
OVERDOSAGE
Lethal doses can cause muscle twitching, spasms, tachycardia and cyanosis through asphyxiation. Following gastric lavage, poisonings are treated with atropine; in the case of spasms, diazepam is also used. Forced diuresis can be useful. The lethal dose for an adult is 6 to 10 mg. |
Byron J. Richards, CCN
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 High levels of Apo E are a primary risk factor for developing alzheimer's disease.
While being overweight does not necessarily cause Alzheimer's, it certainly tilts body chemistry in a direction that increases one's risk for the disease, especially if a person has genetic predisposition to the problem.
A recent study with dogs demonstrated that air pollution activates all of the above inflammatory factors and leads to changes in the brain consistent with alzheimer's disease.722 Similarly, exposure to aluminum produces the same elevation of NF kappaB and TNFa leading to damaged brain cells. |
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